It provides for the legal, unlicensed citation or incorporation of copyrighted material in another author's work under a four-factor balancing test. Examples of fair use include commentary, search engines, criticism, news reporting, research, teaching, library archiving and scholarship. In United States copyright law, fair use is a doctrine that permits limited use of copyrighted material without acquiring permission from the rights holders. If you are the author of the text above and you not agree to share your knowledge for teaching, research, scholarship (for fair use as indicated in the United States copyrigh low) please send us an e-mail and we will remove your text quickly.įair use is a limitation and exception to the exclusive right granted by copyright law to the author of a creative work. (biochemistry) Proteins that bring together various other proteins in a signaling pathway and allow for their interaction. In the case of metabolic enzymes, protein scaffolding drives metabolic flux through specific pathways by colocalizing enzyme active sites. The effect of these complexes and the response to signals can be different depending on the subcellular localization of the complex. Meaning and definition of scaffolding protein :Ī type of large relay protein to which several other relay proteins are simultaneously attached to increase the efficiency of signal transduction.įor the term scaffolding protein may also exist other definitions and meanings, the meaning and definition indicated above are indicative not be used for medical and legal or special purposes.Īuthor : not indicated on the source document of the above text Protein scaffolding is a natural phenomenon whereby proteins colocalize into macromolecular complexes via specific proteinprotein interactions. The organization of signaling complexes on scaffold proteins is dynamic, and there is an order of assembly that may vary depending on the input signal. The information of medicine and health contained in the site are of a general nature and purpose which is purely informative and for this reason may not replace in any case, the council of a doctor or a qualified entity legally to the profession. The best-known example of scaffold protein is MEKK1 protein. After binding, the scaffold protein tethers these multiple proteins into complexes. A scaffold ideally permits the attachment, differentiation, and maturation of cells in a specified manner, mimicking the 3D cytoarchitecture of meat while. A contig is a contiguous length of genomic sequence in which the order of bases is known to a high confidence level. Scaffolds are composed of contigs and gaps.
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The following texts are the property of their respective authors and we thank them for giving us the opportunity to share for free to students, teachers and users of the Web their texts will used only for illustrative educational and scientific purposes only.Īll the information in our site are for educational uses. Scaffold protein is a large protein that interacts with multiple proteins of a signalling pathway in order to regulate signal transduction. What is a Scaffold A scaffold is a portion of the genome sequence reconstructed from end-sequenced whole-genome shotgun clones.
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